CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.450 | Nuclear Transport Factor 2; Chain: A, |
|
3.10.450.50 |
Domain Context
CATH Clusters
| Superfamily | 3.10.450.50 |
| Functional Family |
Enzyme Information
| 3.3.2.8 |
Limonene-1,2-epoxide hydrolase.
based on mapping to UniProt Q9ZAG3
1,2-epoxymenth-8-ene + H(2)O = menth-8-ene-1,2-diol.
-!- Involved in the monoterpene degradation pathway of the actinomycete Rhodococcus erythropolis. -!- The enzyme hydrolyzes several alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide. -!- It differs from the previously described epoxide hydrolases (EC 3.3.2.4, EC 3.3.2.6, EC 3.3.2.7, EC 3.3.2.9 and EC 3.3.2.10) as it is not inhibited by 2-bromo-4'-nitroacetophenone, diethyl pyrocarbonate, 4-fluorochalcone oxide or 1,10-phenanthroline.
|
UniProtKB Entries (1)
| Q9ZAG3 |
LIMA_RHOER
Rhodococcus erythropolis
Limonene-1,2-epoxide hydrolase
|
PDB Structure
| PDB | 4R9K |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
X-ray crystallographic validation of structure predictions used in computational design for protein stabilization.
Proteins
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