CATH Classification

Domain Context

CATH Clusters

Superfamily 6.10.130.20
Functional Family

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O43683
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O43683
BUB1_HUMAN
Homo sapiens
Mitotic checkpoint serine/threonine-protein kinase BUB1

PDB Structure

PDB 4R8Q
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and substrate recruitment of the human spindle checkpoint kinase Bub1.
Kang, J., Yang, M., Li, B., Qi, W., Zhang, C., Shokat, K.M., Tomchick, D.R., Machius, M., Yu, H.
Mol.Cell