CATH Classification

Domain Context

CATH Clusters

Superfamily DNA polymerase, thumb domain
Functional Family DNA nucleotidylexotransferase

Enzyme Information

2.7.7.31
DNA nucleotidylexotransferase.
based on mapping to UniProt P09838
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes template-independent extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Nucleoside may be ribo- or deoxyribo-.

UniProtKB Entries (1)

P09838
TDT_MOUSE
Mus musculus
DNA nucleotidylexotransferase

PDB Structure

PDB 4QZI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.
Gouge, J., Rosario, S., Romain, F., Poitevin, F., Beguin, P., Delarue, M.
Embo J.