CATH Classification

Domain Context

CATH Clusters

Superfamily DNA polymerase, Y-family, little finger domain
Functional Family DNA polymerase IV

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q47155
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q47155
DPO4_ECOLI
Escherichia coli K-12
DNA polymerase IV

PDB Structure

PDB 4Q45
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Unique structural features in DNA polymerase IV enable efficient bypass of the N2 adduct induced by the nitrofurazone antibiotic
Kottur, J., Sharma, A., Gore, K.R., Narayanan, N., Samanta, B., Pradeepkumar, P.I., Nair, D.T.
Structure