CATH Classification

Domain Context

CATH Clusters

Superfamily 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q5NGA7
Q5NGA7_FRATT
Francisella tularensis subsp. tularensis SCHU S4
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase

PDB Structure

PDB 4PZV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural enzymology and inhibition of the bi-functional folate pathway enzyme HPPK-DHPS from the biowarfare agent Francisella tularensis.
Shaw, G.X., Li, Y., Shi, G., Wu, Y., Cherry, S., Needle, D., Zhang, D., Tropea, J.E., Waugh, D.S., Yan, H., Ji, X.
Febs J.