CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family receptor-type tyrosine-protein phosphatase delta isoform X1

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q13332
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q13332
PTPRS_HUMAN
Homo sapiens
Receptor-type tyrosine-protein phosphatase S

PDB Structure

PDB 4PBX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.
Coles, C.H., Mitakidis, N., Zhang, P., Elegheert, J., Lu, W., Stoker, A.W., Nakagawa, T., Craig, A.M., Jones, E.Y., Aricescu, A.R.
Nat Commun