1 keywords

CATH Domain 4ov4A01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family

Enzyme Information

UniProtKB Entries (1)

B0SN40
B0SN40_LEPBP
Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'
2-isopropylmalate synthase (Alpha-isopropylmalate synthase Alpha-IPM synthetase)

PDB Structure

PDB 4OV4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition.
Zhang, Z., Wu, J., Lin, W., Wang, J., Yan, H., Zhao, W., Ma, J., Ding, J., Zhang, P., Zhao, G.P.
J.Biol.Chem.