CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.120.1770
Functional Family Cytochrome b reductase 1

Enzyme Information

7.2.1.3
Ascorbate ferrireductase (transmembrane).
based on mapping to UniProt Q9SWS1
Ascorbate(Side 1) + Fe(III)(Side 2) = monodehydroascorbate(Side 1) + Fe(II)(Side 2).
-!- A diheme cytochrome that transfers electrons across a single membrane, such as the outer membrane of the enterocyte, or the tonoplast membrane of the plant cell vacuole. -!- Acts on hexacyanoferrate(III) and other ferric chelates. -!- Formerly EC 1.16.5.1.

UniProtKB Entries (1)

Q9SWS1
ACFR2_ARATH
Arabidopsis thaliana
Probable transmembrane ascorbate ferrireductase 2

PDB Structure

PDB 4O79
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase
Lu, P., Ma, D., Yan, C., Gong, X., Du, M., Shi, Y.
Proc.Natl.Acad.Sci.USA