CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O14976
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O14976
GAK_HUMAN
Homo sapiens
Cyclin-G-associated kinase

PDB Structure

PDB 4O38
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the human cyclin G associated kinase (GAK)
Zhang, R., Hatzos-Skintges, C., Weger, A., Chaikuad, A., Eswaran, J., Fedorov, O., King, O., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S., Joachimiak, A.
To be Published