CATH Classification

Domain Context

CATH Clusters

Superfamily Pantoate-beta-alanine ligase, C-terminal domain
Functional Family Pantothenate synthetase

Enzyme Information

6.3.2.1
Pantoate--beta-alanine ligase (AMP-forming).
based on mapping to UniProt P9WIL4
ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.

UniProtKB Entries (1)

P9WIL4
PANC_MYCTO
Mycobacterium tuberculosis CDC1551
Pantothenate synthetase

PDB Structure

PDB 4MUG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Optimization of Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase Based on Group Efficiency Analysis.
Hung, A.W., Silvestre, H.L., Wen, S., George, G.P., Boland, J., Blundell, T.L., Ciulli, A., Abell, C.
Chemmedchem