CATH Classification

Domain Context

CATH Clusters

Superfamily Bromodomain-like
Functional Family Bromodomain-containing protein 4

Enzyme Information

UniProtKB Entries (1)

O60885
BRD4_HUMAN
Homo sapiens
Bromodomain-containing protein 4

PDB Structure

PDB 4MR4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain.
Picaud, S., Wells, C., Felletar, I., Brotherton, D., Martin, S., Savitsky, P., Diez-Dacal, B., Philpott, M., Bountra, C., Lingard, H., Fedorov, O., Muller, S., Brennan, P.E., Knapp, S., Filippakopoulos, P.
Proc.Natl.Acad.Sci.USA