CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Ribosomal protein S6 kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P18654
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P18654
KS6A3_MOUSE
Mus musculus
Ribosomal protein S6 kinase alpha-3

PDB Structure

PDB 4M8T
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Covalent docking of large libraries for the discovery of chemical probes.
London, N., Miller, R.M., Krishnan, S., Uchida, K., Irwin, J.J., Eidam, O., Gibold, L., Cimermancic, P., Bonnet, R., Shoichet, B.K., Taunton, J.
Nat.Chem.Biol.