CATH Classification

Domain Context

CATH Clusters

Superfamily Dam replacing family, catalytic PD-(D/E)XK domain
Functional Family

Enzyme Information

3.1.21.4
Type II site-specific deoxyribonuclease.
based on mapping to UniProt P0A459
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/

UniProtKB Entries (1)

P0A459
T2D1_STRPN
Streptococcus pneumoniae TIGR4
Type-2 restriction enzyme DpnI

PDB Structure

PDB 4KYW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of the methylation specificity of R.DpnI.
Mierzejewska, K., Siwek, W., Czapinska, H., Kaus-Drobek, M., Radlinska, M., Skowronek, K., Bujnicki, J.M., Dadlez, M., Bochtler, M.
Nucleic Acids Res.