CATH Classification

Domain Context

CATH Clusters

Superfamily Haloacid dehalogenase hydrolase-like domain
Functional Family N-acylneuraminate-9-phosphatase

Enzyme Information

3.1.3.29
N-acylneuraminate-9-phosphatase.
based on mapping to UniProt Q8TBE9
N-acylneuraminate 9-phosphate + H(2)O = N-acylneuraminate + phosphate.

UniProtKB Entries (1)

Q8TBE9
NANP_HUMAN
Homo sapiens
N-acylneuraminate-9-phosphatase

PDB Structure

PDB 4KNW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: Observation of extensive dynamics in an enzyme/inhibitor complex.
Kim, S.H., Constantine, K.L., Duke, G.J., Goldfarb, V., Hunt, J.T., Johnson, S., Kish, K., Klei, H.E., McDonnell, P.A., Metzler, W.J., Mueller, L., Poss, M.A., Fairchild, C.R., Bhide, R.S.
Bioorg.Med.Chem.Lett.