CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1000 | HAD superfamily/HAD-like |
Domain Context
CATH Clusters
| Superfamily | HAD superfamily/HAD-like |
| Functional Family | N-acylneuraminate-9-phosphatase |
Enzyme Information
| 3.1.3.29 |
N-acylneuraminate-9-phosphatase.
based on mapping to UniProt Q8TBE9
N-acylneuraminate 9-phosphate + H(2)O = N-acylneuraminate + phosphate.
|
UniProtKB Entries (1)
| Q8TBE9 |
NANP_HUMAN
Homo sapiens
N-acylneuraminate-9-phosphatase
|
PDB Structure
| PDB | 4KNW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: Observation of extensive dynamics in an enzyme/inhibitor complex.
Bioorg.Med.Chem.Lett.
|