CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.630 | Aminopeptidase |
|
3.40.630.30 | Gcn5-related N-acetyltransferase (GNAT) |
Domain Context
CATH Clusters
| Superfamily | 3.40.630.30 |
| Functional Family | N-acetylglutamate synthase, mitochondrial |
Enzyme Information
| 2.3.1.1 |
Amino-acid N-acetyltransferase.
based on mapping to UniProt Q8N159
Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate.
-!- Also acts with L-aspartate and, more slowly, with some other amino acids.
|
UniProtKB Entries (1)
| Q8N159 |
NAGS_HUMAN
Homo sapiens
N-acetylglutamate synthase, mitochondrial
|
PDB Structure
| PDB | 4K30 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of the N-acetyltransferase domain of human N-acetyl-L-glutamate synthase in complex with N-acetyl-L-glutamate provides insights into its catalytic and regulatory mechanisms.
Plos One
|