CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family N-acetylneuraminate lyase

Enzyme Information

4.1.3.3
N-acetylneuraminate lyase.
based on mapping to UniProt Q9CKB0
N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate.
-!- Also acts on N-glycoloylneuraminate, and on O-acetylated sialic acids, other than 4-O-acetylated derivatives.

UniProtKB Entries (1)

Q9CKB0
NANA_PASMU
Pasteurella multocida subsp. multocida str. Pm70
N-acetylneuraminate lyase

PDB Structure

PDB 4IMG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis for Substrate Specificity and Mechanism of N-Acetyl-d-neuraminic Acid Lyase from Pasteurella multocida.
Huynh, N., Aye, A., Li, Y., Yu, H., Cao, H., Tiwari, V.K., Shin, D.W., Chen, X., Fisher, A.J.
Biochemistry