CATH Classification

Domain Context

CATH Clusters

Superfamily SIR2/SIRT2 'Small Domain'
Functional Family NAD-dependent deacetylase sir2A

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt P06700

UniProtKB Entries (1)

P11978
SIR4_YEAST
Saccharomyces cerevisiae S288C
Regulatory protein SIR4

PDB Structure

PDB 4IAO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for allosteric stimulation of Sir2 activity by Sir4 binding
Hsu, H.C., Wang, C.L., Wang, M., Yang, N., Chen, Z., Sternglanz, R., Xu, R.M.
Genes Dev.