CATH Classification

Domain Context

CATH Clusters

Superfamily 3.60.21.10
Functional Family Serine/threonine-protein phosphatase

Enzyme Information

3.1.3.16
Protein-serine/threonine phosphatase.
based on mapping to UniProt P67775
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).

UniProtKB Entries (1)

Q9Y5P8
P2R3B_HUMAN
Homo sapiens
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta

PDB Structure

PDB 4I5N
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Wlodarchak, N., Guo, F., Satyshur, K.A., Jiang, L., Jeffrey, P.D., Sun, T., Stanevich, V., Mumby, M.C., Xing, Y.
Cell Res.