CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.270
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q4JB80
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q4JB80
DPO4_SULAC
Sulfolobus acidocaldarius DSM 639
DNA polymerase IV

PDB Structure

PDB 4HYK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Y-family polymerase conformation is a major determinant of fidelity and translesion specificity.
Wilson, R.C., Jackson, M.A., Pata, J.D.
Structure