CATH Classification

Domain Context

CATH Clusters

Superfamily PAS domain
Functional Family Hypoxia-inducible factor 1-alpha isoform 1

Enzyme Information

UniProtKB Entries (1)

Q99814
EPAS1_HUMAN
Homo sapiens
Endothelial PAS domain-containing protein 1

PDB Structure

PDB 4GS9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Development of Inhibitors of the PAS-B Domain of the HIF-2 alpha Transcription Factor
Rogers, J.L., Bayeh, L., Scheuermann, T.H., Longgood, J., Key, J., Naidoo, J., Melito, L., Shokri, C., Frantz, D.E., Bruick, R.K., Gardner, K.H., Macmillan, J.B., Tambar, U.K.
J.Med.Chem.