CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.630 | Aminopeptidase |
|
3.40.630.30 | Gcn5-related N-acetyltransferase (GNAT) |
Domain Context
CATH Clusters
| Superfamily | 3.40.630.30 |
| Functional Family | Alpha-tubulin N-acetyltransferase 1 |
Enzyme Information
| 2.3.1.108 |
Alpha-tubulin N-acetyltransferase.
based on mapping to UniProt Q5SQI0
Acetyl-CoA + [alpha-tubulin]-L-lysine = CoA + [alpha-tubulin]-N(6)- acetyl-L-lysine.
-!- The enzyme from Chlamydomonas flagella also acetylates mammalian brain alpha-tubulin.
|
UniProtKB Entries (1)
| Q5SQI0 |
ATAT_HUMAN
Homo sapiens
Alpha-tubulin N-acetyltransferase 1
|
PDB Structure
| PDB | 4GS4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of the alpha-tubulin acetyltransferase, alpha TAT1, and implications for tubulin-specific acetylation.
Proc.Natl.Acad.Sci.USA
|