CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.120 | Enolase-like C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Enolase-like C-terminal domain |
| Functional Family |
Enzyme Information
| 5.5.1.27 |
D-galactarolactone cycloisomerase.
based on mapping to UniProt A9CEQ8
(1) D-galactaro-1,4-lactone = 5-dehydro-4-deoxy-D-glucarate. (2) D-glucaro-1,4-lactone = 5-dehydro-4-deoxy-D-glucarate.
-!- The enzyme, characterized from the bacterium Agrobacterium fabrum strain C58, is involved in degradation of D-galacturonate and D-glucuronate. -!- Activity with D-galactaro-1,4-lactone is 4-fold higher than with D-glucaro-1,4-lactone.
|
UniProtKB Entries (1)
| A9CEQ8 |
GCI_AGRFC
Agrobacterium fabrum str. C58
D-galactarolactone cycloisomerase
|
PDB Structure
| PDB | 4GGB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Purification, crystallization and structural elucidation of D-galactaro-1,4-lactone cycloisomerase from Agrobacterium tumefaciens involved in pectin degradation.
Acta Crystallogr.,Sect.F
|