CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.367.20
Functional Family Hexokinase 1

Enzyme Information

2.7.1.1
Hexokinase.
based on mapping to UniProt P19367
ATP + D-hexose = ADP + D-hexose 6-phosphate.
-!- D-glucose, D-mannose, D-fructose, sorbitol and D-glucosamine can act as acceptors. -!- ITP and dATP can act as donors.

UniProtKB Entries (1)

P19367
HXK1_HUMAN
Homo sapiens
Hexokinase-1

PDB Structure

PDB 4FPB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Inhibitor Sites of Unequal Affinity Linked by Binding Synergism in Mutant Forms of Recombinant Human Hexokinase Type-I
Shen, L., Gao, Y., Honzatko, R.B.
to be published