CATH Classification

Domain Context

CATH Clusters

Superfamily Lyase 2-enoyl-coa Hydratase, Chain A, domain 2
Functional Family Probable enoyl-CoA hydratase, mitochondrial

Enzyme Information

4.2.1.17
Enoyl-CoA hydratase.
based on mapping to UniProt P9WNN9
(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O.
-!- Acts in the reverse direction. -!- With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74).

UniProtKB Entries (1)

P9WNN9
ECHA8_MYCTU
Mycobacterium tuberculosis H37Rv
Probable enoyl-CoA hydratase echA8

PDB Structure

PDB 4FJW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure and Mechanism of the Prokaryotic Crotonase
Bruning, J.B., Delgado, E., Ghosh, S., Sacchettini, J.C.
To be Published