CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.3.1.44
Trans-2-enoyl-CoA reductase (NAD(+)).
based on mapping to UniProt Q73Q47
Acyl-CoA + NAD(+) = trans-didehydroacyl-CoA + NADH.
-!- The enzyme from Euglena gracilis acts on crotonoyl-CoA and, more slowly, on trans-hex-2-enoyl-CoA and trans-oct-2-enoyl-CoA.

UniProtKB Entries (1)

Q73Q47
FABV_TREDE
Treponema denticola ATCC 35405
Trans-2-enoyl-CoA reductase [NADH]

PDB Structure

PDB 4FBG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
Hu, K., Zhao, M., Zhang, T., Zha, M., Zhong, C., Jiang, Y., Ding, J.
Biochem.J.