CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family

Enzyme Information

3.8.1.5
Haloalkane dehalogenase.
based on mapping to UniProt P0A3G2
1-haloalkane + H(2)O = a primary alcohol + halide.
-!- Acts on a wide range of 1-haloalkanes, haloalcohols, haloalkenes and some haloaromatic compounds.

UniProtKB Entries (1)

P0A3G2
DHAA_RHORH
Rhodococcus rhodochrous
Haloalkane dehalogenase

PDB Structure

PDB 4F5Z
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel.
Koudelakova, T., Chaloupkova, R., Brezovsky, J., Prokop, Z., Sebestova, E., Hesseler, M., Khabiri, M., Plevaka, M., Kulik, D., Kuta Smatanova, I., Rezacova, P., Ettrich, R., Bornscheuer, U.T., Damborsky, J.
Angew.Chem.Int.Ed.Engl.