CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family serine/threonine-protein kinase TBK1 isoform X1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q9UHD2
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q9UHD2
TBK1_HUMAN
Homo sapiens
Serine/threonine-protein kinase TBK1

PDB Structure

PDB 4EUU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation.
Ma, X., Helgason, E., Phung, Q.T., Quan, C.L., Iyer, R.S., Lee, M.W., Bowman, K.K., Starovasnik, M.A., Dueber, E.C.
Proc.Natl.Acad.Sci.USA