CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family KRAS proto-oncogene, GTPase

Enzyme Information

UniProtKB Entries (1)

P01116
RASK_HUMAN
Homo sapiens
GTPase KRas

PDB Structure

PDB 4EPW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation.
Sun, Q., Burke, J.P., Phan, J., Burns, M.C., Olejniczak, E.T., Waterson, A.G., Lee, T., Rossanese, O.W., Fesik, S.W.
Angew.Chem.Int.Ed.Engl.