CATH Domain 4e36A01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1730	tricorn interacting facor f3 domain

Domain Context

CATH Clusters

Superfamily	tricorn interacting facor f3 domain
Functional Family	Endoplasmic reticulum aminopeptidase 2

Enzyme Information

3.4.11.-

Aminopeptidases.

based on mapping to UniProt Q6P179

UniProtKB Entries (1)

ERAP2_HUMAN

Homo sapiens

Endoplasmic reticulum aminopeptidase 2

PDB Structure

PDB	4E36
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing. Evnouchidou, I., Birtley, J., Seregin, S., Papakyriakou, A., Zervoudi, E., Samiotaki, M., Panayotou, G., Giastas, P., Petrakis, O., Georgiadis, D., Amalfitano, A., Saridakis, E., Mavridis, I.M., Stratikos, E. J.Immunol.