CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family

Enzyme Information

3.4.11.21
Aspartyl aminopeptidase.
based on mapping to UniProt Q9ULA0
Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.
-!- Aminoacyl-arylamides are poor substrates. -!- Belongs to peptidase family M18.

UniProtKB Entries (1)

Q9ULA0
DNPEP_HUMAN
Homo sapiens
Aspartyl aminopeptidase

PDB Structure

PDB 4DYO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of human aspartyl aminopeptidase complexed with substrate analogue: insight into catalytic mechanism, substrate specificity and M18 peptidase family.
Chaikuad, A., Pilka, E.S., Riso, A.D., Delft, F.V., Kavanagh, K.L., Venien-Bryan, C., Oppermann, U., Yue, W.W.
Bmc Struct.Biol.