CATH Classification

Domain Context

CATH Clusters

Superfamily HR1 repeat
Functional Family Tyrosine-protein kinase

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P07332
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P07332
FES_HUMAN
Homo sapiens
Tyrosine-protein kinase Fes/Fps

PDB Structure

PDB 4DYL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
F-BAR domain of human FES tyrosine kinase
Ugochukwu, E., Salah, E., Elkins, J., Barr, A., Krojer, T., Filippakopoulos, P., Weigelt, J., Arrowsmith, C.H., Edwards, A., Bountra, C., von Delft, F., Knapp, S., Structural Genomics Consortium (SGC)
TO BE PUBLISHED