CATH Classification

Domain Context

CATH Clusters

Superfamily Complement Module, domain 1
Functional Family mannan-binding lectin serine protease 1 isoform X2

Enzyme Information

3.4.21.-
Serine endopeptidases.
based on mapping to UniProt P48740

UniProtKB Entries (1)

P48740
MASP1_HUMAN
Homo sapiens
Mannan-binding lectin serine protease 1

PDB Structure

PDB 4DJZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2.
Heja, D., Harmat, V., Fodor, K., Wilmanns, M., Dobo, J., Kekesi, K.A., Zavodszky, P., Gal, P., Pal, G.
J.Biol.Chem.