CATH Classification

Domain Context

CATH Clusters

Superfamily ornithine cyclodeaminase, domain 1
Functional Family Ketimine reductase mu-crystallin

Enzyme Information

1.5.1.25
Thiomorpholine-carboxylate dehydrogenase.
based on mapping to UniProt O54983
Thiomorpholine 3-carboxylate + NAD(P)(+) = 3,4-dehydro-thiomorpholine-3- carboxylate + NAD(P)H.
-!- The product is the cyclic imine of the 2-oxoacid corresponding to S-(2-aminoethyl)cysteine. -!- In the reverse direction, a number of other cyclic unsaturated compounds can act as substrates, more slowly.

UniProtKB Entries (1)

O54983
CRYM_MOUSE
Mus musculus
Ketimine reductase mu-crystallin

PDB Structure

PDB 4BV9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Mouse Mu-Crystallin Complexed with Nadph and the T3 Thyroid Hormone
Borel, F., Hachi, I., Palencia, A., Gaillard, M.C., Ferrer, J.L.
FEBS J.