CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent RNA helicase DDX6

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P39517
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

P39517
DHH1_YEAST
Saccharomyces cerevisiae S288C
ATP-dependent RNA helicase DHH1

PDB Structure

PDB 4BRU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Analysis of the Yeast Dhh1-Pat1 Complex Reveals How Dhh1 Engages Pat1, Edc3 and RNA in Mutually Exclusive Interactions
Sharif, H., Ozgur, S., Sharma, K., Basquin, C., Urlaub, H., Conti, E.
Nucleic Acids Res.