CATH Classification

Domain Context

CATH Clusters

Superfamily Calcium-transporting ATPase, cytoplasmic transduction domain A
Functional Family Copper-exporting P-type ATPase A

Enzyme Information

7.2.2.8
P-type Cu(+) transporter.
based on mapping to UniProt Q5ZWR1
ATP + H(2)O + Cu(+)(Side 1) = ADP + phosphate + Cu(+)(Side 2).
-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC 7.2.2.9, which mainly transports the divalent copper ion. -!- Formerly EC 3.6.3.54.

UniProtKB Entries (1)

Q5ZWR1
COPA_LEGPH
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Copper-exporting P-type ATPase

PDB Structure

PDB 4BBJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Copper-Transporting P-Type Atpases Use a Unique Ion-Release Pathway
Andersson, M., Mattle, D., Sitsel, O., Klymchuk, T., Nielsen, A., Moller, L.B., White, S.H., Nissen, P., Gourdon, P.
Nat.Struct.Mol.Biol.