CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family L-lactate dehydrogenase

Enzyme Information

1.1.1.27
L-lactate dehydrogenase.
based on mapping to UniProt Q71T02
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.

UniProtKB Entries (1)

Q71T02
Q71T02_PLAFA
Plasmodium falciparum
L-lactate dehydrogenase

PDB Structure

PDB 4B7U
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Crystal Structure of Plasmodium Falciparum L- Lactate Dehydrogenase in Complex with a Novel Bicine Ligand
Birkinshaw, R.W., Brady, R.L.
To be Published