CATH Domain 4aybP00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.20	Single Sheet
	2.20.28	Rubrerythrin, domain 2
	2.20.28.30	RNA polymerase ii, chain L

Domain Context

CATH Clusters

Superfamily	RNA polymerase ii, chain L
Functional Family

Enzyme Information

2.7.7.6

DNA-directed RNA polymerase.

based on mapping to UniProt B8YB64

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

-!- Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized. -!- See also EC 2.7.7.19 and EC 2.7.7.48.

UniProtKB Entries (1)

B8YB61

B8YB61_SACSH

Saccharolobus shibatae B12

DNA-directed RNA polymerase subunit K

PDB Structure

PDB	4AYB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and Functional Analyses of the Interaction of Archaeal RNA Polymerase with DNA. Wojtas, M.N., Mogni, M., Millet, O., Bell, S.D., Abrescia, N.G.A. Nucleic Acids Res.