CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Ephrin type-A receptor 5

Enzyme Information

2.7.10.1
Receptor protein-tyrosine kinase.
based on mapping to UniProt P54762
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P54762
EPHB1_HUMAN
Homo sapiens
Ephrin type-B receptor 1

PDB Structure

PDB 3ZFX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Completing the Structural Family Portrait of the Human Ephb Tyrosine Kinase Domains
Overman, R.C., Debreczeni, J.E., Truman, C.M., Mcalister, M.S., Attwood, T.K.
Protein Sci.