CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Dynamin-1-like protein isoform 1

Enzyme Information

3.6.5.5
Dynamin GTPase.
based on mapping to UniProt O00429
GTP + H(2)O = GDP + phosphate.
-!- An enzyme with a molecular mass of about 100 kDa that is involved in endocytosis and is instrumental in pinching off membrane vesicles. -!- Formerly EC 3.6.1.50.

UniProtKB Entries (1)

O00429
DNM1L_HUMAN
Homo sapiens
Dynamin-1-like protein

PDB Structure

PDB 3W6N
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of GTPase domain fused with minimal stalks from human dynamin-1-like protein (Dlp1) in complex with several nucleotide analogues
Kishida, H., Sugio, S.
CURR TOP PEPT PROTEIN RES.