CATH Classification

Domain Context

CATH Clusters

Superfamily Glycogen Phosphorylase B;
Functional Family

Enzyme Information

2.5.1.135
Validamine 7-phosphate valienyltransferase.
based on mapping to UniProt Q15JG1
GDP-valienol + validamine 7-phosphate = validoxylamine A 7'-phosphate + GDP.
-!- The enzyme, characterized from several Streptomyces strains, is involved in the biosynthesis of the antifungal agent validamycin A.

UniProtKB Entries (1)

Q15JG1
VLDE_STRHL
Streptomyces hygroscopicus subsp. limoneus
Validamine 7-phosphate valienyltransferase

PDB Structure

PDB 3VDM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of VldE, the pseudo-glycosyltransferase which catalyzes non-glycosidic C-N coupling in Validamycin A biosynthesis
Cavalier, M.C., Yim, Y.-S., Asamizu, S., Neau, D., Mahmud, T., Lee, Y.-H.
To be Published