CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Twitchin

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q23551
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q23551
UNC22_CAEEL
Caenorhabditis elegans
Twitchin

PDB Structure

PDB 3UTO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase.
von Castelmur, E., Strumpfer, J., Franke, B., Bogomolovas, J., Barbieri, S., Qadota, H., Konarev, P.V., Svergun, D.I., Labeit, S., Benian, G.M., Schulten, K., Mayans, O.
Proc.Natl.Acad.Sci.USA