CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family glutaminase kidney isoform, mitochondrial

Enzyme Information

3.5.1.2
Glutaminase.
based on mapping to UniProt O94925
L-glutamine + H(2)O = L-glutamate + NH(3).

UniProtKB Entries (1)

O94925
GLSK_HUMAN
Homo sapiens
Glutaminase kidney isoform, mitochondrial

PDB Structure

PDB 3UO9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Full-length human glutaminase in complex with an allosteric inhibitor.
DeLaBarre, B., Gross, S., Fang, C., Gao, Y., Jha, A., Jiang, F., Song J, J., Wei, W., Hurov, J.B.
Biochemistry