CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Serine/threonine-protein kinase pim-1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P11309
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P11309
PIM1_HUMAN
Homo sapiens
Serine/threonine-protein kinase pim-1

PDB Structure

PDB 3UIX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A novel pim-1 kinase inhibitor targeting residues that bind the substrate Peptide.
Tsuganezawa, K., Watanabe, H., Parker, L., Yuki, H., Taruya, S., Nakagawa, Y., Kamei, D., Mori, M., Ogawa, N., Tomabechi, Y., Handa, N., Honma, T., Yokoyama, S., Kojima, H., Okabe, T., Nagano, T., Tanaka, A.
J.Mol.Biol.