CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family protein disulfide-isomerase A2

Enzyme Information

5.3.4.1
Protein disulfide-isomerase.
based on mapping to UniProt P07237
Catalyzes the rearrangement of -S-S- bonds in proteins.
-!- Needs reducing agents or partly reduced enzyme; the reaction depends on sulfhydryl-disulfide interchange.

UniProtKB Entries (1)

P07237
PDIA1_HUMAN
Homo sapiens
Protein disulfide-isomerase

PDB Structure

PDB 3UEM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Human protein-disulfide isomerase is a redox-regulated chaperone activated by oxidation of domain a'
Wang, C., Yu, J., Huo, L., Wang, L., Feng, W., Wang, C.-C.
J.Biol.Chem.