CATH Classification

Domain Context

CATH Clusters

Superfamily K Homology domain, type 1
Functional Family Polyribonucleotide nucleotidyltransferase 1, mitochondrial

Enzyme Information

2.7.7.8
Polyribonucleotide nucleotidyltransferase.
based on mapping to UniProt Q8TCS8
RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.
-!- ADP, IDP, GDP, UDP and CDP can act as donors.

UniProtKB Entries (1)

Q8TCS8
PNPT1_HUMAN
Homo sapiens
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

PDB Structure

PDB 3U1K
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of human polynucleotide phosphorylase: insights into its domain function in RNA binding and degradation
Lin, C.L., Wang, Y.-T., Yang, W.-Z., Hsiao, Y.-Y., Yuan, H.S.
Nucleic Acids Res.