CATH Classification

Domain Context

CATH Clusters

Superfamily Bira Bifunctional Protein; Domain 2
Functional Family Phenylalanyl-tRNA synthetase 2, mitochondrial

Enzyme Information

6.1.1.20
Phenylalanine--tRNA ligase.
based on mapping to UniProt O95363
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl- tRNA(Phe).

UniProtKB Entries (1)

O95363
SYFM_HUMAN
Homo sapiens
Phenylalanine--tRNA ligase, mitochondrial

PDB Structure

PDB 3TUP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Human Mitochondrial PheRS Complexed with tRNA(Phe) in the Active "Open" State.
Klipcan, L., Moor, N., Finarov, I., Kessler, N., Sukhanova, M., Safro, M.G.
J.Mol.Biol.