CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Quinate/shikimate dehydrogenase

Enzyme Information

1.1.1.25
Shikimate dehydrogenase.
based on mapping to UniProt Q8Y9N5
Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
-!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.

UniProtKB Entries (1)

Q8Y9N5
AROE_LISMO
Listeria monocytogenes EGD-e
Shikimate dehydrogenase (NADP(+))

PDB Structure

PDB 3TOZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
2.2 Angstrom Crystal Structure of Shikimate 5-dehydrogenase from Listeria monocytogenes in Complex with NAD.
Minasov, G., Light, S.H., Halavaty, A., Shuvalova, L., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
TO BE PUBLISHED