CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.1490.310
Functional Family Serine/threonine-protein kinase BRI1-like 1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O22476
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
2.7.10.1
Receptor protein-tyrosine kinase.
based on mapping to UniProt O22476
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

O22476
BRI1_ARATH
Arabidopsis thaliana
Protein BRASSINOSTEROID INSENSITIVE 1

PDB Structure

PDB 3RIZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of steroid hormone perception by the receptor kinase BRI1.
Hothorn, M., Belkhadir, Y., Dreux, M., Dabi, T., Noel, J.P., Wilson, I.A., Chory, J.
Nature