CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family

Enzyme Information

2.1.1.-
Methyltransferases.
based on mapping to UniProt Q9NRG4
2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9NRG4
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q9NRG4
SMYD2_HUMAN
Homo sapiens
N-lysine methyltransferase SMYD2

PDB Structure

PDB 3RIB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins
Xu, S., Zhong, C., Zhang, T., Ding, J.
J Mol Cell Biol